1:
The ideal Google AdSense page should have grand content about a very distinctive topic. Take pains to be very clear about what the topic is, and carefully choose the keyword (or key phrase) describing the topic. Users do not like vague pages that do not contruct it very clear what the page is all about.

Do not even ruminate on trying to trick AdSense. (They have penalties, including acquiring kicked out.) Dont create a page on one topic and give it a document title about a different topicthats too confusing.

In a nutshell, you want to build sure the page you create offers great assessment of value to many people interested in the topic. When you provide excellent data on a targeted topic, your visitors will benefit and will be more likely to click through to relevant AdWords.

2:
Everyones seen way too many horizontal banner ads up top. Thus, Google recommends you choose the vertical -- not horizontal -- format to display your AdWords. I agree. People have become "banner blind" to a horizontal format. Plus, Google has "trained" us to click on relevant writing ads on their own site and they use the vertical format.

3:
Its to your financial advantage to put the AdWords near the top of your page on the right. Make sure there is enough "breathing room" -- i.e. white space around the ads -- so that they will easily attract your visitors.

4:
The latest branding tests have revealed that affixing pictures beside, or above youre a ads may have a massive impact on click-thru rates. This is because the eye is immediately attracted to the photo , once they see the picture, they see the ad!

5:
I know its tempting, because it seems so easy and its just sitting there standing around for you to do it, but do not click on the AdWords displayed on your own site to increase your revenue. Google (rightfully) frowns on this.

Plus, Google has some of the smartest engineers around, and they are very sizeably effective at detecting this kind of fraud. And really, for an more $1, is it worth taking kicked out of a money-maker like AdSense? I think not